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Clinical Director, Stony Brook University School of Medicine

A variant of multiple sclerosis: rapid demyelination of the optic nerve & spinal cord w/ paraplegia 356 prehypertension spanish order clonidine amex. Astrocytoma (including Glioblastoma Multiforme) then: mets heart attack one direction lyrics order clonidine 0.1 mg fast delivery, meningioma, Schwannoma 410. Fibrocystic Change: premenopausic women (Carcinoma is the most common in post-menopausal women) 412. Dilated (Congestive) Cardiomyopathy: Alcohol, BeriBeri, Cocaine use, Coxsackie B, Doxorubicin 424. Multiple Sclerosis: (Charcot Triad = nystagmus, intention tremor, scanning speech) 463. Immunologic (Bence Jones protein in multiple myeloma is also called the Amyloid Light Chain) 474. Adult polycystic kidney disease: associated w/ polycystic liver, Berry aneurysms, Mitral prolapse 485. Mixed Cellularity (versus: lymphocytic predominance, lymphocytic depletion, nodular sclerosis) 552. Sonnei Page 13 Paraphilia Metabolite seen w/ Pheochromocytoma Severe Shigella Bug in Otitis Media & Sinusitis in Kids Cause of a Solitary Brain Abscess Cause of Bacterial Diarrhea in U. Shigella Type Cause of Non-Ghonococcal Urethritis Pneumonia Urethritis Cause of Glomerulonephritis Cause of Viral Pneumonia 576. At low doses Txt Shock= dilates renal and mesenteric aa= maintain urine output 12. Txt Malignant Ventricular Arrhythmias but causes passing catecholamine release that can aggravate arrhythmias briefly 23. Does not discriminate b/t fibrin-based clots= bleeding & stroke complications arise 33. Captopril/ Enalapril Cause renal failure = use w/ caution in the elderly contraction rate & force via 1. Theophyline) Favored for the Txt of Reentrant Supra Ventricular Tachycardia Low molecular weight heparin = Oral anticoagulant 63. Txt lennox gestaut seizures in kids Butyrophenone Atypical D4 Flumazenil Methylphenidate Phenytoin Thiopental Carbamazepine Atypical D4-r Pimozide Risperidone Thioridazine Haloperidol 10. Can be used in combo w/ Fentanyl for neuroleptoanalgesic effect Neuroleptic tranquilizer. Has mild alpha block Can be used on combo w/ Droperidol for neuroleptoanalgesic effect Used transdermally for chronic pain Pre anesthetic. Accumulates in keratinized layers of the skin = used in dermatomycoses infections 55. Aureus) "Red neck": due to histamine release causes facial flushing used w/ Cilastatin Does not cause seizures (cf w/ Imipenem) Only penicillin that does not need dose adjustment in renal impairment 72. Aka infiltrative cardiomyopathy that stiffens the heart Due to amyloidosis in the elderly Due to , also see schaumann & asteroid bodies in young (<25 yoa). Petehial hemorrhages are seen on kidney surfaces = Flea-Bitten surface = young black men 146. Hemosiderin (pigment w/ Fe3-) covered macrophages that have been pahgocytised 166. Tapeworm infection causing megaloblastic anemia by consuming large amount of vit B12 in the host 229. Zones of medial necrosis +/- slitlike cysts = Medial Cystic Necrosis of Erdheim 241. Complicaitons: pleural effusion; atelectasia; fibrinous pleuritis; empyema; fibrinous pericarditis; otitis media 250.

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What preventative measures does your agency have in place regarding driving an ambulance to decrease the risk of ambulance crashes A science and consensus-based national guideline that recommends 24 core criteria for all mass casualty triage systems c hypertension headaches symptoms purchase cheap clonidine on-line. It refers to the extent to which individuals and groups will commit to personal responsibility for safety; act to preserve blood pressure medication can you get off generic clonidine 0.1mg line, enhance and communicate safety concerns; strive to actively learn, adapt and modify (both individual and organizational) behavior based on lessons learned from mistakes; and be rewarded in a manner consistent with these values. Assess risks in order to identify means of overcoming factors that contribute to errors 1. Systems factors and individual factors are examined in order to make improvements to avoid future errors iii. A robust, secure system would allow access to researchers, decision makers, and national stakeholder groups. Continuing education and new employee onboarding must infuse culture of safety throughout the curricula. Safety standards for patient and responder safety must be developed using data and evidence ii. Mandates for reporting safety are necessary so a common language and data set can be created to improve responder and patient safety 1. Identifying existing best practices Consider these questions in regards to the policies, practices, and daily operations in your organization/agency: a. All ambulances should have seats and restraints appropriate for securing children from newborn on up b. Child seats/restraints should only be attached to cots, cot mounts and restraints that have been tested and comply with standards of J3027 d. Child seats/restraints should only be attached to seating positions that pass the appropriate standard when tested as a system together. Situation 1: For a child who is uninjured/not ill (child who is accompanying an injured or ill patient) i. Situation 2: For a child who is ill and/or injured and whose condition does not require continuous and/or intensive medical monitoring and/or interventions i. Situation 3 For a child whose condition requires continuous and/or intensive medical monitoring and/or interventions 1. Situation 4: For a child whose condition requires spinal immobilization or lying flat i. Head first, with a tether at the foot (if possible) to prevent forward movement 2. Situation 5: For a child or children who require transport as part of a multiple patient transport (newborn with mother, multiple children, etc. When possible, transport each as a single patient according to the guidance shown for Situations 1through 4. Discuss the ongoing initiatives to increase the safety of children during ambulance transport a. To recommend the criteria or specifications for proper restraint of children in ambulances. Such criteria will be evidence-based and will consider safety of both patients and providers ii. To have the recommended criteria adopted by one or more accredited standard setting organizations. Available research on child- restraint systems only rates the safety in normal use, not in ambulances b. Not enough evidence from research on simulated ambulance crashes involving child restraint systems to recommend evidence-based guidelines c. Effectively using all resources in an effort to minimize errors, improve safety, and improve performance. Their mission is "preventing accident by improving crew performance through better crew coordination. Created to optimize human performance by reducing the effect of human error through the use of all resources, including: i. Collective team knowledge and experience should be utilized to make a 77 decision iv. Team leader is ultimate authority on final decision but relies on input from all members with equal weight, incorporating experience and knowledge of team c. Tasks should be divided among all team members to optimize functioning of team as a whole ii.

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At the same time pulse pressure fitness buy clonidine 0.1 mg with mastercard, the liver starts cobbling together new molecules of glucose from bits and pieces of other nutrients in the body hypertension vasoconstriction order 0.1mg clonidine otc. Also, because a person may not be able to eat, insulin doses at mealtime may not be taken, leading to insulin deficiency. A third factor is dehydration, which can come along with vomiting and inadequate fluid consumption. Other people purposefully skip insulin doses for weight management purposes, particularly adolescent girls. Fluids: High glucose spills into the urine, drawing out water and minerals and causing high urine output at the beginning. Unless a person is able to drink enough fluids on their own, giving fluids through an intravenous line will be needed. Adults are more tolerant of fluids and are generally given a fairly large amount (1 L) initially to help them return to normal. Insulin: At the same time the fluids are given, an intravenous line with insulin in it will be started. The insulin will be directly dripped into the vein so it can act quickly to turn off ketone production and restore the body to normal. Even if starting levels are high or normal, the potassium levels can fall, and this is very serious because adequate potassium levels are required for a normal heartbeat. Treating the cause: If there is an infection, such as a bladder infection or pneumonia, this needs to be treated. Older adults may be having a heart attack or other serious problem, so the team in the emergency room will need to carefully check out all the possible problems that can be happening at the same time. Once treatment is started, a person starts to feel much better within a few hours. The vomiting and headache (caused by the ketones) stop, normal urine flow returns, and the person "comes back to life. Sometimes it is hard to recognize increased thirst and urination in kids because they are still in diapers, are at school using the water fountain and restroom on their own, or are teenagers and private about these matters. If there is another family member with type 1 diabetes, children and adults can be screened for the antibodies in the blood that are associated with developing type 1 diabetes. If the antibodies are positive, then the family knows that they are at risk of developing type 1 diabetes and can be on the lookout for symptoms. On Day 9 "On the day we began a cross-country move, our 15-month-old vomited all over the airport terminal. After all, we did take him to the pediatrician after a few days and were told it was a virus. Four more days of training with a team of educators and we were sent home with an insulin pump on our toddler. While in the hospital, I feared that my happy, easygoing boy would never be the same, but John was playing with his sister within minutes of getting home. Six months later, we just returned from a family vacation full of airplanes, water parks, and even ice cream. Unfortunately, the latter situation happens far too often in underserved regions of the U. Sometimes young adults and sometimes older adults simply rebel and stop giving enough insulin. A pharmacy can give you regular insulin (a vial and syringe) without a prescription if you can prove you have diabetes. Generally you can prove this by bringing in an empty vial of insulin or a pen or your meter-something that shows you have diabetes. You can give a dose of regular insulin every 6 h and keep enough insulin in your body.

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Cardiovascular System 89 Accelerated Hypertension A significant recent increase in blood pressure over previous hypertensive levels hypertension with diabetes buy discount clonidine 0.1 mg on line, associated with evidence of vascular damage on fundoscopic examination hypertensive urgency treatment purchase clonidine 0.1 mg otc, but without papilloedema. Labile Hypertension Patients who sometimes, but not always have arterial pressure within the hypertensive range, are classified as having labile hypertension. The cuff is then deflated even more slowly, and the pressure is again noted when Korotkoff sound becomes audible throughout the respiratory cycle. Normally the difference between the two pressures should not exceed 10 mm Hg during quiet respiration. Paradox: Heart sounds are still heard over the precordium at a time when no pulse is palpable at the radial artery. Transient Hypertension this may be seen in Acute cerebrovascular accidents Acute myocardial infarction Acute glomerulonephritis Pregnancy Acute intermittent porphyria. It is systemic hypertension seen for a transient phase of time when the patient is under stress or when he is having a disorder with a transient hypertensive phase, as may occur in the above-mentioned conditions. However, a patient with pheochromocytoma may be normotensive, hypotensive or hypertensive. Pulsus alternans is present if there is an alteration in the intensity of Korotkoff sound. The right internal jugular vein is selected because it is larger, straighter and has no valves. Thus, the vertical height of the column of blood in the neck can be estimated from the sternal angle, to which 5 cm is added to obtain an estimate of mean right atrial pressure in centimeters of blood. This estimation may be erroneous in patients with deformed chest walls or malpositioning of the heart. Markers of Rheumatic Fever Joint swelling (Migrating polyarthritis involving major joints, leaving no residual deformities) Erythema marginatum Subcutaneous nodules. Abdominal Jugular Reflux Firm compression is given in the periumbilical area for 30 seconds. Abdominal jugular reflux is positive in right or left heart failure and/or tricuspid regurgitation. In the absence of these conditions, a positive abdominal jugular reflux suggests an elevated pulmonary artery wedge or central venous pressure. In congenital heart disease look for: Cyanosis Clubbing Polycythaemia Hypertelorism Low set ears High arched palate Webbed neck Syndactyly, Polydactyly, Arachnodactyly (Polydactyly: Trisomy 13 to 1 and 18. Precordial bulge indicates the presence of right ventricular hypertrophy presenting since early childhood. Pulmonary artery pulsation Apical Impulse Apical impulse is the lower most and outer most point of definite cardiac impulse with a maximum perpendicular thrust to the palpating finger. Normal apical impulse is produced by left ventricle and the left ventricular portion of the interventricular septum. Suprasternal pulsation Supraclavicular pulsation 94 Manual of Practical Medicine. Golden Rules Before commenting on the position and character of apical impulse, look for the presence of chest wall or spinal deformities, and the tracheal position. When the apical impulse is not localisable on the left side, palpate the right hemithorax for its presence (dextrocardia or pseudo-dextrocardia) 3. Tapping apical impulse Behind the rib or sternum Dextrocardia Palpable S1 (closing snap). Heaving apical impulse is one in which there is increase in both amplitude and duration. Parasternal impulse can be seen in Right ventricular enlargement or Left atrial enlargement Causes of Right Ventricular Enlargement Volume overload: Fast, ill-sustained parasternal impulse- Left to right shunts. Left Atrial Enlargement Left atrial enlargement is seen in mitral stenosis and mitral regurgitation.

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Much of the substance use uses the term substance misuse arteria srl clonidine 0.1 mg with mastercard, a term that is roughly equivalent to substance disorder data included in this Report is based on definitions abuse hypertension medication drugs buy clonidine 0.1mg with mastercard. Anyone meeting one driving), use that leads a person to fail to fulfill responsibilities or gets them or more of the abuse criteria-which focused largely on the in legal trouble, or use that continues negative consequences associated with substance misuse, despite causing persistent interpersonal such as being unable to fulfill family or work obligations, problems like fights with a spouse. Instead, substance misuse is now the preferred which included symptoms of drug tolerance, withdrawal, term. Although misuse is not a escalating and uncontrolled substance use, and the use of diagnostic term, it generally suggests the substance to the exclusion of other activities, would use in a manner that could cause harm receive the "dependence" diagnosis. Individuals are evaluated for a substance to produce the same effect achieved use disorder based on 10 or 11 (depending on the substance) during initial use. Individuals exhibiting fewer than two of the symptoms use of a substance to which a person has become dependent or addicted, are not considered to have a substance use disorder. Those which can include negative emotions exhibiting two or three symptoms are considered to have such as stress, anxiety, or depression, a "mild" disorder, four or five symptoms constitutes a as well as physical effects such as "moderate" disorder, and six or more symptoms is considered nausea, vomiting, muscle aches, and cramping, among others. Tolerance and withdrawal remain major clinical symptoms, but they are no longer the deciding factor in whether an individual "has an addiction. It does not refer to an arranged meeting or confrontation intended to persuade a friend or loved one to quit their substance misuse or enter treatment-the type of "intervention" sometimes depicted on television. Planned surprise confrontations of the latter variety-a model developed in the 1960s, sometimes called the "Johnson Intervention"-have not been demonstrated to be an effective way to engage people in treatment. It is also important to understand that substance use disorders do not occur immediately but over time, with repeated misuse and development of more symptoms. This means that it is both possible and highly advisable to identify emerging substance use disorders, and to use evidence-based early interventions to stop the addiction process before the disorder becomes more chronic, complex, and difficult to treat. This type of proactive clinical monitoring and management is already done within general health care settings to address other potentially progressive illnesses that are brought about by unhealthy behaviors. Typically, these individuals are also clinically monitored for key symptoms to ensure that symptoms do not worsen. There are compelling reasons to apply similar procedures in emerging cases of substance misuse. Routine screening for alcohol and other substance use should be conducted in primary care settings to identify early symptoms of a substance use disorder (especially among those with known risk and few protective factors). This should be followed by informed clinical guidance on reducing the frequency and amount of substance use, family education to support lifestyle changes, and regular monitoring. Nonetheless, it is possible to adopt the same 1 type of chronic care management approach to the treatment of substance use disorders as is now used to manage most other chronic illnesses. This fact is supported by a national survey showing that there are more than 25 million individuals who once had a problem with alcohol or drugs who no longer do. For these reasons, a new system of substance use disorder treatment programs was created, but with administration, regulation, and financing placed outside mainstream health care. Of equal historical importance was the decision to focus treatment only on addiction. This left few provisions for detecting or intervening clinically with the far more prevalent cases of early-onset, mild, or moderate substance use disorders. Creating this system of substance use disorder treatment programs was a critical element in addressing the burgeoning substance use disorder problems in our nation. However, that separation also created unintended and enduring impediments to the quality and range of care options. For example, separate systems for substance use disorder treatment and other health care needs may have exacerbated the negative public attitudes toward people with substance use disorders. Additionally, the pharmaceutical industry was hesitant to invest in the development of new medications for individuals with substance use disorders, because they were not convinced that a market for these medications existed. A recent study showed that the presence of a substance use disorder often doubles the odds for the subsequent development of chronic and expensive medical illnesses, such as arthritis, chronic pain, heart disease, stroke, hypertension, diabetes, and asthma. Moreover, few medical, nursing, dental, or pharmacy schools teach their students about substance use disorders;83-86 and, until recently, few insurers offered adequate reimbursement for treatment of substance use disorders. The Affordable Care Act requires the majority of United States health plans and insurers to offer prevention, screening, brief interventions, and other forms of treatment for substance use disorders. These laws and related changes in health care financing are creating incentives for health care organizations to integrate substance use disorder treatment with general health care. Many questions remain, but those questions are no longer whether but how this much-needed integration will occur. These changes combine to create a new, challenging but exceptionally promising era for the prevention and treatment of substance use disorders and set the context for this Report.

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